United States securities and exchange commission logo May 13, 2020 Daniel P. Gold, Ph.D. President & Chief Executive Officer MEI Pharma, Inc. 3611 Valley Centre Drive, Suite 500 San Diego, California 92130 Re: MEI Pharma, Inc. Registration Statement on Form S-3 Filed May 7, 2020 File No. 333-238056 Dear Dr. Gold: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Irene Paik at 202-551-6553 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Finnbarr D. Murphy